profane

Definition:

To profane something means to act in a way that defiles, pollutes, or disrespects something that is holy.

A profane person is one who acts in a way that is unholy and dishonoring of God.
The verb "to profane" could be translated as "to treat as unholy" or "to be irreverent toward" or "to dishonor."
God told the Israelites that they "profaned" themselves with idols, meaning that the people were making themselves "unclean" or "dishonored" by this sin. They were also dishonoring God.
Depending on the context, the adjective "profane" could be translated as "dishonoring" or "godless" or "unholy."

(See also: defile · holy · unclean)