desecrate

Definition:

The term "desecrate" means to damage or contaminate a sacred place or object in such a way that it is unacceptable for use in worship.

Often desecrating something involves showing great disrespect for it.
For example, pagan kings desecrated special dishes from God's temple by using them for parties at their palace.
Bones from dead people were used by enemies to desecrate the altar in God's temple.
This term could be translated as "cause to be unholy" or "dishonor by making impure" or "disrespectfully profane" or "cause to be impure."