RobH_en_tn/rev/16/06.md

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they poured out the blood of the saints and prophets

Here "poured out the blood" means killed. Alternate translation: "they murdered God's holy people and the prophets" (See: rc://en/ta/man/translate/figs-metonymy)

you have given them blood to drink

God will make the evil people drink the waters that he turned to blood.