General Information:

John begins to describe the part of his vision about the great prostitute.

the condemnation of the great prostitute

The noun "condemnation" can be expressed with the verb "condemn." AT: "how God will condemn the great prostitute" (See: rc://en/ta/man/translate/figs-abstractnouns)

"the prostitute that everyone knows about." She represents a certain sinful city. (See: rc://en/ta/man/translate/writing-symlanguage)

If you need to, you can use a more specific word for the kind of water. AT: "on many rivers" (See: rc://en/ta/man/translate/figs-explicit)

The wine represents sexual immorality. AT: "The people of the earth became drunk by drinking her wine, that is, they were sexually immoral" (See: rc://en/ta/man/translate/figs-distinguish and rc://en/ta/man/translate/writing-symlanguage)

This may well have a double meaning: sexual immorality among people and also the worship of false gods. (See: rc://en/ta/man/translate/figs-metaphor)