Paul is implying that he and Timothy are working with God. Alternate translation: "Working together with God" (See: [[rc://en/ta/man/translate/figs-explicit]])
Paul pleads with them to allow the grace of God to be effective in their lives. This can be stated in positive terms. Alternate translation: "we beg you to make use of the grace that you have received from God" (See: [[rc://en/ta/man/translate/figs-doublenegatives]])