"Weighing down" represents the idea of putting a very heavy load on a person so he cannot move freely. This phrase means to make a person sad or depressed. Alternate translation: "causes him to become sad or depressed" (See: [[rc://en/ta/man/translate/figs-metaphor]])
The abstract noun "word" can be stated as the verb "speak." Alternate translation: "but when others speak kindly to him, he is cheerful again" (See: [[rc://en/ta/man/translate/figs-abstractnouns]])