Yahweh uses rhetorical questions to rebuke Sennacherib. Alternate translation: "You have defied and insulted me! You have exalted your voice and lifted up your eyes in pride against me, the Holy One of Israel!" (See: [[rc://en/ta/man/translate/figs-rquestion]])
"lifted up your eyes in pride" is metonymy for a haughty or arrogant facial expression. Alternate translation: "looked at very proudly" (See: [[rc://en/ta/man/translate/figs-metonymy]])