This rhetorical question emphasizes the futility of making evil plans against Yahweh. Alternate translation: "It is futile for you people to plot against Yahweh" (See: [[rc://en/ta/man/translate/figs-rquestion]])
The idiom "make a full end" refers to causing something to exist no longer. Alternate translation: "He will completely stop what you do" or "He will cause your plotting to fail" (See: [[rc://en/ta/man/translate/figs-idiom]])
Possible meanings are 1) "trouble" is a metonym for the punishment that Yahweh will inflict upon the people. Alternate translation: "Yahweh will not have to punish you a second time" or 2) "trouble" refers to the trouble that the people cause by plotting against Yahweh. Alternate translation: "you will not cause trouble a second time" (See: [[rc://en/ta/man/translate/figs-metonymy]])