Here the briars and thorns represent what would cause suffering and pain. Alternate translation: "people anywhere around the house of Israel who wound them like briars, hurt them like thorns, and despise them" (See: [[rc://en/ta/man/translate/figs-metaphor]])
The word "house" is a metonym for the family that lives in the house. In this case it refers to Israel's descendants. See how you translated this in [Ezekiel 3:1](../03/01.md). Alternate translation: "the Israelites" or "the Israelite people group" (See: [[rc://en/ta/man/translate/figs-metonymy]])